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1. Cotton Tufts papers, 1751-1805 (inclusive)

2. Correspondence from Edward Augustus Holyoke to Susanna Holyoke, 1792 September 28

3. Correspondence from Edward Augustus Holyoke to Charles Blagden, 1794 May 31

4. Medical bill from Edward Augustus Holyoke to Joshua Pico, 1776 November 23

5. Medical bill from Edward Augustus Holyoke to Mary Turner Bowditch, 1782 August 17

6. Medical bill from Edward Augustus Holyoke to William Northey, 1793 December 17

7. Medical bill from Edward Augustus Holyoke to Benjamin Shillabar, 1800 January 6

8. Manuscript on smallpox inoculation by Edward Augustus Holyoke, undated